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David R. Santiago-Dieppa, M.D.



  • M.D. Johns Hopkins University
  • B.S. University of California, Riverside


Dr. Santiago-Dieppa started his residency in neurological surgery at the University of California San Diego in 2013. He is an Alpha Omega Alpha graduate of the Johns Hopkins University School of Medicine, where he was first introduced to the field of neurological surgery under the guidance of Dr. Timothy F. Witham and Dr. Henry Brem. Prior to receiving his medical degree, he received his BS in biochemistry, Magna Cum Lade, from the University of California Riverside. 

Dr. Santiago-Dieppa’s research interests are in the fields of cerebrovascular, skull base, spine, and medical device development. He will be completing an endovascular neurosurgery fellowship from 2016 to 2018, and upon completion of his residency training he will be pursuing an academic career.
When he is not in the hospital, he spends his time with his wife Rosa and their two small children.  

Selected Publications:

Beran GJ, Chronister EL, Daemen LL, Moehlig AR, Mueller LJ, Oomens J, Rice A, Santiago-Dieppa DR, Tham FS, Theel K,  Yaghmaei S, Morton TH. Vibrations of a chelated proton in a Protonated tertiary diamine. Phys Chem Chem Phys. 2011 Dec 7;13(45):20380-92. PubMed PMID: 21993532

Chaichana KL, Bydon M, Santiago-Dieppa DR, Hwang L, McLoughlin G, Sciubba DM, Wolinsky JP, Bydon A, Gokaslan ZL, Witham T. Risk of infection following posterior instrumented lumbar fusion for degenerative spine disease in 817 consecutive cases. J Neurosurg Spine. 2014 PubMed PMID: 24206038.

Lina IA, Puvanesarajah V, Liauw JA, Lo SF, Santiago-Dieppa DR, Hwang L, Mao A, Bydon A, Wolinsky JP, Sciubba DM, Gokaslan Z, Holmes C, Witham TF. Quantitative study of parathyroid hormone (1-34) and bone morphogenetic protein-2 on spinal fusion outcomes in a rabbit model of lumbar dorsolateral intertransverse process arthrodesis. Spine (Phila Pa 1976). 2014 PubMed PMID: 24365898.

Parker SL, Amin AG, Santiago-Dieppa  DR, Liauw JA, Bydon A, Sciubba DM, Wolinsky JP, Gokaslan ZL, Witham TF. Incidence and Clinical Significance of Vascular Encroachment Resulting from Free Hand Placement of Pedicle Screws in the Thoracic and Lumbar Spine: Analysis of 6,816 Consecutive Screws. Spine (Phila Pa 1976). 2014] PubMed PMID: 24480963.

Bydon M, Xu R, Santiago-Dieppa DR, Macki M, Sciubba DM, Wolinsky JP, Bydon A, Gokaslan ZL, Witham TF. Adjacent-segment disease in 511 cases of posterolateral instrumented lumbar arthrodesis: floating fusion versus distal construct including the sacrum. J Neurosurg Spine. 2014 PubMed PMID: 24484304.

Santiago-Dieppa D, Bydon M, Xu R, De la Garza-Ramos R, Henry R, Sciubba DM,Wolinsky JP, Bydon A, Gokaslan ZL, Witham TF. Long-term outcomes after non-instrumented lumbar arthrodesis. J Clin Neurosci. 2014 PubMed PMID: 24831342.

Scott Pannell J, Santiago-Dieppa DR, Khalessi AA. Interventional management of acute ischemic stroke: a systematic review. Curr Treat Options Cardiovasc Med. 2014 PubMed PMID: 24919838.

Santiago-Dieppa DR, Pannell JS, Khalessi AA. Endovascular and surgical options for ruptured middle cerebral artery aneurysms: review of the literature. Stroke Res Treat. 2014 PubMed PMID: 25097795; PubMed Central PMCID: PMC4109112.

Santiago-Dieppa DR, Steinberg J, Gonda D, Cheung VJ, Carter BS, Chen CC. Extracellular vesicles as a platform for 'liquid biopsy' in glioblastoma patients. Expert Rev Mol Diagn. 2014 PubMed PMID: 25136839; PubMed Central PMCID: PMC4436244.

Santiago-Dieppa DR, Hwang LS, Bydon A, Gokaslan ZL, McCarthy EF, Witham TF. L4 and L5 spondylectomy for en bloc resection of giant cell tumor and review of the literature. Evid Based Spine Care J. 2014 PubMed PMID: 25364329; PubMed Central PMCID: PMC4212699.

Walker CT, Amene CS, Pannell JS, Santiago-Dieppa DR, Rennert RC, Hansen LA, Khalessi AA. Hemorrhagic intramedullary solitary fibrous tumor of the conus medullaris: case report. J Neurosurg Spine. 2015 PMID: 26115022.

Rennert RC, Santiago-Dieppa DR, Pannell JS, Khalessi AA. Management of Ruptured and Rapidly Progressive Mycotic Cerebral Aneurysms in the Setting ofUnilateral Carotid Occlusion and Endocarditis with Valve Failure. J Neurol SurgRep. 2015 Nov;76(2):e222-6. doi: 10.1055/s-0035-1555748. Epub 2015 Aug 3. PubMed PMID: 26623231

Santiago-Dieppa DR, Zhou T, Jones KA, Gabel BC, Chen JY, Hansen L, U HS. Intracranial Rhabdomyoma: Case Report and Review of the Literature. Cureus. 2016 Apr 29;8(4):e593. doi: 10.7759/cureus.593. PubMed PMID: 27335706; PubMed Central PMCID: PMC4914064.       

Rennert RC, Santiago-Dieppa DR, Figueroa J, Sanai N, Carter BS. Futuredirections of operative neuro-oncology. J Neurooncol. 2016 Jun 22. [Epub ahead ofprint] Review. PubMed PMID: 27334902.

Santiago-Dieppa DR, Wali A R, Gabel B C, et al. (August 01, 2016) The Inter-Mammary Sticky Roll: A Novel Technique for Securing a Doppler Ultrasonic Probe to the Precordium for Venous Air Embolism Detection. Cureus 8(8): e719. doi:10.7759/cureus.719 PubMed PMID: Pending

Selected Awards:

  • Graduate, Summer Medical & Dental Education Program University of Washington School of Medicine, Seattle, WA (2006)
  • Recipient, Chicano Educational and Cultural Fund, Inc scholarship in academic excellence and community service. (2006)                                
  • Recipient, The Affiliates of UCR Raymond and Alberta Palmer Scholarship, in recognition of high academic achievement and demonstration of outstanding promise. (2007)      
  • Recipient, Dr. W. Moti Pre-Med Student Award, In recognition of scholastic achievement and service to the community. (2008)
  • Recipient, UCR Honors Convocation Medal Recognizing Scholarship, Leadership, Excellence, & Achievement. (2008 & 2009)             
  • Recipient, UCR Rosemary J. Schruer Award, The highest honor the College of Natural and Agricultural Sciences bestows upon a graduating senior. (2009)                              
  • Member, Phi Beta Kappa, IOTA Chapter (2009)
  • Recipient, Harvey Cushing Medical Student Research Award, In recognition of contributions to the advancement of neurological sciences. Johns Hopkins University School of Medicine. (2012)
  • Recipient, Alpha Omega Alpha Honor Society (2013) Johns Hopkins University School of Medicine.